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Senolytics are anything that aids the removal of senescent, or aged, cells in the body. Senolytics can be a molecule, a supplement, or a practice like fasting. Senolytics represent the cutting edge of anti-aging technology. Researchers are making great progress understanding the process by which our cells break down and take themselves out of commission, and how this relates to aging and disease.
In short, senescent cells are cells that are injured, stressed, diseased, irregular, or just plain old. A healthy, young body regularly eliminates these cells through the processes of autophagy and apoptosis. As we age, however, these processes can’t keep up, and aged cells that are not properly cleared and removed cause aging and age-related diseases like cancer.
In this sense, senolytic supplements are geroprotectors – by enabling the removal of senescent cells, they protect us against aging. Scientists are currently exploring natural senolytic foods like quercetin, as well as senolytic activator drugs like dasatinib. All of this research holds great promise in helping humanity slow and defeat the aging process.